‘Yes, which is about ideal. I hunt for a Actual physical understanding of biological devices in a bottom-up way. I feel you can distinguish 3 strains of research in my group at the moment. The initial problems chromosome composition: How can you get yourself a metre-very long DNA polymer folded and organised in this kind of microscopic cell? We've got designed visualisation procedures that permit us to study how, such as, SMC proteins loop DNA (video on Youtube) as a way to Create up chromosomes.
1996, to start with mesoscopic charge density waves products; and first electrical measurements on just one metallic nanocluster between nanoelectrodes
Dynamics of initiation, termination and reinitiation of DNA translocation by the motor protein EcoR124I
I can rarely visualize how I, to be a geneticist, would manage to master essential physics, not to mention compete at the top. How did you go over it?
We establish place-of-care diagnostics test of neglected tropical diseases in just source-restricted configurations, based upon Crspr/Cas9 detecting of pathogen’s DNA in entire body fluids.
The coiled-coil of the human Rad50 DNA repair service protein contains distinct segments of elevated adaptability
MATLAB codes for knowledge processing are available at . Julia codes useful for numerical simulation can be found at .
Illustration (1) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in grey, the rim of the pore is highlighted in crimson, and a 3D rendering on the motion on the DNA rod is displayed.
In 1993, as a younger and keen affiliate professor at Delft University of Engineering, I'd in the beginning focused the analysis initiatives of my team on measuring the electrical conductance of a single conducting-polymer molecule. Inside of two yrs, we had developed a tool where a single wire of a phthalocyaninepolysiloxane polymer was connected amongst two intently spaced metallic nanoelectrodes.
But carbon nanotubes have remained a investigate subject matter of sizeable desire to lots of. In truth, the outlook on applying carbon nanotubes to make realistic products, in regions for example radio-frequency electronics, digital electronics and flexible electronics, continues to be dazzling.
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
Afterwards we spoke once more briefly due to the fact Dekker felt that our dialogue of his religion quickly became purely philosophical, While Additionally, it concretely aids him in his get the job done.
Permit’s to start with look back in the mean time if you made a decision to change your concentration from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.
The biophysicist from Delft – who continues to be cees dekker Probably the most cited scientists during the Netherlands For several years – requires his responsibility to add to your clarification and popularisation of his function at the border of physics and biology exceptionally severely and often appears in the media; Otherwise to speak about his function, then about the connection amongst science and his Christian faith.